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特发性震颤的中医证素及其组化规律研究
赵文博,卜献春
0
(湖南省中医药研究院附属医院,湖南 长沙,410006)
摘要:
目的:通过大宗病例资料研究,归纳出特发性震颤辨证论治的一般规律。方法:收集2005年9月至2016年12月于本院门诊就诊的符合纳入标准的特发性震颤病例资料。采用SPSS 16.0对病例资料的临床症状、证素等进行频数分析、主成分分析、聚类分析、相关性分析,对使用中药进行多维尺度分析,研究特发性震颤常见证素、证素组合、用药规律,探讨特发性震颤的辨证论治方法。结果:97例病例资料统计,得到10个常见证素中的“肝风”,“阴虚、精亏、阳亢”,“痰浊、瘀血”3种证素组合;中药多维尺度分析,得到“燥湿化痰”“活血化瘀”“滋阴潜阳”和“平肝息风”4种药物组合。从专业角度分析,证素组合与药物组合之间存在内在联系,反映的病机一致。结论:1)特发性震颤的基本病机为“肝风”;2)得到特发性震颤之虚风内动、阴虚阳亢、痰瘀阻络3个证型的证素组成、辨证要点和治疗用药。归纳出特发性震颤辨证论治的一般规律。
关键词:  特发性震颤  中医证素  辨证论治  组化规律
DOI:
Traditional Chinese medicine syndrome elements of essential tremor and the pattern of syndrome element combination
ZHAO Wenbo,BU Xianchun
(The Affiliated Hospital of Hunan Academy of Chinese Medicine,Changsha 410006,Hunan,China)
Abstract:
Objective:To investigate the general rules of syndrome differentiation-based treatment of essential tremor through an analysis of case data.Methods:Clinical data were collected from the patients with essential tremor who attended the outpatient service of our hospital from September 2005 to December 2016 and met the inclusion criteria.SPSS 16.0 was used to perform frequency analysis,principal component analysis,cluster analysis,and correlation analysis of clinical symptoms and syndrome elements,and a multidimensional scaling (MDS) analysis was performed for the traditional Chinese medicine (TCM) drugs used.The common syndrome elements,combination of syndrome elements,and medication rule of essential tremor were analyzed,and the methods for syndrome differentiation based treatment of essential tremor were discussed.Results:The statistical analysis of the clinical data of 97 patients obtained three combinations of ten common syndrome elements,i.e.,“liver wind”,“Yin deficiency,deficiency of essence,and hyperactivity of Yang”,and “phlegm turbidity and blood stasis”.The MDS analysis of TCM drugs obtained four combinations of drugs,i.e.,“dampness-drying and phlegm-eliminating”“blood-activating and stasis-resolving”“Yin nourishing and Yang-suppressing”,and “liver-pacifying and wind-extinguishing”.From the professional point of view,there was an inner connection between combination of syndrome elements and drug combinations,which reflected the same pathogenesis.Conclusion:“Liver wind” is the basic pathogenesis of essential tremor.Syndrome elements,key points of syndrome differentiation,and treatment drugs are obtained for essential tremor with the three syndrome types of endogenous deficient wind,Yin-deficiency and Yang-hyperactivity,and phlegm stasis blocking collaterals.The general rules of syndrome differentiation-based treatment of essential tremor are summarized.
Key words:  essential tremor  traditional Chinese medicine syndrome element  syndrome differentiation-based treatment  pattern of syndrome element combination

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